Xylometazoline HCl
1218-35-5
General information
Xylometazoline is a direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels.
Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.
Trade names
Otrivin, Sinutab, Nasoferm, Nasic
About the API
Therapeutic areas
Decongestant
Monographs
USP, Ph. Eur.
Regulatory documentation
CEP/ USDMF
Production location
Minden
Standard pack size
1kg, 5kg, 10kg
Physical properties
Crystalline substance
Typical formulation types
Nasal topical